Table 2 Predictive performance of in vitro, PET, and clinical indices and their combinations for breast Cancer recurrence.
AUC | 95% LCI | 95% UCI | Sensitivity (%) | Specificity (%) | Accuracy (%) | ppv (%) | npv (%) | |
|---|---|---|---|---|---|---|---|---|
In vitro indices | ||||||||
Prevotella | 0.5417 | 0.3571 | 0.6881 | 81.82 | 47.92 | 51.4 | 15.25 | 95.83 |
IL-1β | 0.6264 | 0.4558 | 0.7948 | 81.82 | 48.96 | 52.34 | 15.52 | 95.92 |
Panel 1 | 0.5758 | 0.3972 | 0.7557 | 81.82 | 48.96 | 52.34 | 15.52 | 95.92 |
PET indices | ||||||||
SUVtumor | 0.6591 | 0.5267 | 0.781 | 72.73 | 64.58 | 65.42 | 19.05 | 95.38 |
SUVVAT | 0.6027 | 0.4034 | 0.7751 | 45.45 | 85.42 | 81.31 | 26.32 | 93.18 |
SUVspleen | 0.6809 | 0.4832 | 0.8419 | 81.82 | 66.67 | 68.22 | 21.95 | 96.97 |
Panel 2 | 0.6941 | 0.5313 | 0.8197 | 81.82 | 63.54 | 65.42 | 20.45 | 96.83 |
Clinical indices | ||||||||
Subtype | 0.6039 | 0.3962 | 0.783 | 63.64 | 66.33 | 66.06 | 17.5 | 94.2 |
Stage | 0.7421 | 0.5987 | 0.878 | 45.45 | 91.84 | 87.16 | 38.46 | 93.75 |
Panel 3 | 0.8139 | 0.713 | 0.9538 | 63.64 | 89.58 | 86.92 | 41.18 | 95.56 |
Combined model | ||||||||
Panel 4 | 0.9025 | 0.8046 | 0.9564 | 100 | 71.88 | 74.77 | 28.95 | 100 |
