Table 3 A comparative data of the operation time, lymphatic duct signal-to-background ratio (SBR), and lymph node SBR on canine mammary tumors with varying concentrations of indocyanine green (ICG). The study included three distinct concentration groups: 0.5 mg/ml (n = 10), 1.0 mg/ml (n = 18), and 2.5 mg/ml (n = 10). The results are presented as mean values and standard deviations, accompanied by their respective 95% confidence intervals for each ICG concentration. Statistically significant differences (p < 0.05, one-way ANOVA with Tukey’s post hoc test) are indicated by different superscripts within a row.

From: Utilization of indocyanine green for intraoperative sentinel lymph node mapping in canine mammary tumors

 

Dose

 

0.5 mg/mL(n=10)

1.0 mg/mL(n=18)

2.5 mg/mL(n=10)

Operation time

in minutes

(Mean ± SD)

7.3 ± 3.8

(95% CI, 3.3–11.3)

4.9 ± 2.2a

(95% CI, 3.5–6.3)

11.4 ± 4.4b

(95% CI, 6.8–16.1)

Lymphatic duct SBR

(Mean ± SD)

2.0 ± 0.3a

(95% CI, 1.7–2.3)

3.9 ± 1.1b

(95% CI, 3.1–4.6)

4.8 ± 1.2b

(95% CI, 3.7–5.9)

Lymph node

SBR

(Mean ± SD)

6.6 ± 4.4

(95% CI, 2.1–11.2)

10.9 ± 4.8a

(95% CI, 6.9–14.9)

4.3 ± 1.1b

(95% CI, 2.9–5.7)

  1. SBR, signal-to-background ratio; CI, confidence interval.
  2. Different superscripts within a row indicate statistically significant differences (p < 0.05)