Fig. 4 | Scientific Reports

Fig. 4

From: Mechanisms of rifaximin inhibition of hepatic fibrosis in mice with metabolic dysfunction associated steatohepatitis through the TLR4/NFκB pathway

Fig. 4

Effect of rifaximin on inflammatory factors and fibrosis indices. Panel (A), serum IL-6 protein level; Panel (B), hepatic IL-6 mRNA level; Panel (C), hepatic IL-1β mRNA level. Panel (D), sirius red staining (scale bar is 100 μm). Panel (E), the mRNA levels of α-SMA. Panel (F), the mRNA levels of TGF-β. Panel (G), the protein expression level of α-SMA. Panel (H), semi-quantitative analysis of the α-SMA protein. **P < 0.01, ****P < 0.0001 compared with the CON group. #P < 0.05, ###P < 0.001, ####P<0.0001 compared with the MCD group.

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