Fig. 7 | Scientific Reports

Fig. 7

From: Mechanisms of rifaximin inhibition of hepatic fibrosis in mice with metabolic dysfunction associated steatohepatitis through the TLR4/NFκB pathway

Fig. 7

Effects of rifaximin on MASH cell models. Panel (A), effect of free fatty acids on cell viability. Panel (B), effect of rifaximin on cell viability. Panel (C), serum IL-6. Panel (D), the mRNA expression level of IL-6. Panel (E), the mRNA expression level of IL-1β. Panel (F), the mRNA expression level of α-SMA and TGF-β. Panel (G), the protein expression levels of α-SMA. Panel (H), the mRNA expression levels of TLR4 and NF-κB. Panel (I), the protein expression levels of TLR4 and NF-κB. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 compared with the CON group. #P < 0.05, ##P < 0.01, ###P<0.001, ####P<0.0001 compared with the FFA group.

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