Fig. 4
From: Mesothelioma cell heterogeneity identified by single cell RNA sequencing
Top 10 important Gene Ontology terms categories of the up-regulated genes identified by GSEA. (A)–(C) Gene Ontology (GO) term annotations in biological process (BP), cellular component (CC), and molecular function (MF) categories were identified using GSEA (https://www.gsea-msigdb.org/gsea/login.jsp). The top 10 important GO term annotations for cultured cells (CC) (A), circulating tumor cells (CTC) (B), and peritoneal lavage cells (Lav) (C) were determined. GO terms in each group are unique, with no overlap among the three groups. The CC group does not share any GO terms with either the CTC or Lav group. (D)–(F) The CTC and Lav groups exhibit some overlaps: 4 overlaps in biological processes (GO BP) (D), 3 overlaps in cellular components (GO CC) (E), and 6 overlaps in molecular functions (GO MF) (F). Each color represents specific pathways in the group no overlapping with other groups, same as shown in the venn diagrams.
