Table 1 A comparison of the baseline and clinical characteristics of TDDS group and TDS group.

From: Identifying early predictive and diagnostic biomarkers and exploring metabolic pathways for sepsis after trauma based on an untargeted metabolomics approach

Characteristics

TDDS group (N = 50)

TDS group (N = 50)

χ2/t/Z

P-value

Age

48.7 ± 16.6

51.0 ± 15.9

−0.707

0.481

Sex (male, %)

37(74.0)

42(84.0)

1.507

0.220

ISS

19.0(16.8–24.0)

29.0(20.0-38.8)

−4.889

<0.001

GCS

15.0(8.0–15.0)

7.00(5.0–15.0)

4.346

<0.001

SOFA

3.0(2.0–5.0)

5.5(4.0–7.0)

−4.955

<0.001

Heart rate (times/min)

96.7 ± 18.4

109.3 ± 23.2

−3.028

0.003

Systolic pressure (mmHg)

131.1 ± 27.2

123.3 ± 31.2

1.325

0.188

Diastolic pressure (mmHg)

79.5 ± 14.6

75.5 ± 19.9

1.153

0.252

Mean arterial pressure (mmHg)

96.7 ± 17.9

91.4 ± 22.9

1.282

0.203

Respiratory rate (times/min)

20.0(19.8–22.0)

21.0(20.0–25.0)

−1.185

0.239

Pulse oxygen saturation (%)

93.5(87.0–96.0)

94.0(85.8–98.0)

0.749

0.456

WBC (103/mm3)

17.1(12.6–20.3)

17.4(12.3–24.5)

−0.651

0.517

ANC (103/mm3)

14.6(11.4–17.0)

14.7(9.7–21.3)

−0.579

0.564

RBC (104/mm3)

4.1(3.8–4.5)

3.8(2.9–4.3)

2.096

0.005

HGB (g/L)

125.5 ± 24.1

111.9 ± 27.6

2.615

0.010

CREA (umol/L)

67.1(56.1–79.9)

69.2(60.7–85.4)

−2.191

0.032

TBIL (mmol/L)

16.3 ± 8.2

12.7 ± 6.8

2.369

0.020

Alb (g/ml)

34.7(31.1–39.2)

32.9(23.8–38.0)

2.101

0.038

CHE (U/L)

6038.0(5185.5-6794.5)

5541.5(4126.3–6630.0)

2.202

0.030

GLU (mmol/L)

8.8 ± 3.1

10.8 ± 5.0

−2.453

0.016

FIB (g/L)

2.4(1.8–2.8)

1.7(1.4–2.8)

1.847

0.355

D-dimer (ug/mL)

35.6(9.7–43.2)

38.3(17.5–80.5)

−1.709

0.092

LAC (mmol/L)

2.7(1.8–3.5)

3.3(1.8–5.7)

−1.724

0.088

BE (mmol/L)

-4.1(-6.0-2.1)

-5.5(-8.6-3.0)

2.014

0.047

Invasive MV (n, %)

11(22.0)

44(88.0)

44.000

<0.001

Catheterization in DV (n, %)

15(30.0)

29(58.0)

8.536

0.003

Admission to ICU (n, %)

25(50.0)

47(94.0)

24.008

<0.001

Co‑morbidities (n, %)

16(32.0)

18(36.0)

0.123

0.726

Hemorrhagic shock (n, %)

12(30.0)

27(54.0)

8.167

0.004

Open wound (n, %)

29(58.0)

34(68.0)

1.073

0.300

Injury mechanism (n, %)

Traffic accident

37(74.0)

36(72.0)

3.680

0.159

Fall

11(22.0)

7(14.0)

Others

2(4.0)

7(14.0)

Head and neck (n, %)

32(64.0)

40(80.0)

3.175

0.075

Face (n, %)

16(32.0)

14(28.0)

0.190

0.663

Breast (n, %)

42(84.0)

39(78.0)

0.585

0.444

Abdomen (n, %)

25(50.0)

22(44.0)

0.361

0.548

Respiration dysfunction (n, %)

42(84.0)

43(86.0)

0.078

0.779

Circulation dysfunction (n, %)

4(8.0)

15(30.0)

7.862

0.005

Liver dysfunction (n, %)

1(2.0)

6(12.0)

3.840

0.117

kidney dysfunction (n, %)

3(6.0)

15(30.0)

9.756

0.002

Coagulation dysfunction (n, %)

20(40.0)

37(74.0)

11.791

0.001

Nerve dysfunction (n, %)

9(18.0)

6(12.0)

0.706

0.401

LOS in ICU (d)

1.50(0.0-9.3)

15.5(9.8–27.0)

−7.219

<0.001

TLOS (d)

19.0(14.0–23,3)

28.0(22.8–38.5)

−4.115

<0.001

  1. ISS injury severity score, GCS Glasgow coma scale, SOFA sequential organ failure assessment, WBC white blood cell, ANC absolute neutrophil count, RBC red blood cell, HGB haemoglobin, CREA creatinine, TBIL total bilirubin, Alb albumin, CHE cholinesterase, GLU glucose, FIB fibrinogen, LAC lactic acid, BE base excess, MV mechanical ventilation, DV deep vein, LOS length of stay, TLOS total length of stay.
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