Fig. 3

Evaluation of the role of IRS in BRCA patients. (A) The C-index of IRS and clinical characteristics in TCGA, METABRIC and 5 GEO datasets. (B, C) Prognostic risk factors identified by univariate and multivariate cox regression analysis. (D) Nomogram developed based on IRS and clinical characters. (E) Calibration evaluated the role of nomogram in evaluating the prognosis of BRCA patients.