Fig. 2

Conceptual overview of the individual variability of functional connectivity (IVFC) between the DMN and other cerebral regions. (A) The individual variability. There are extensive behavioral differences among individuals, and behavioral differences are partially represented by differences in the brain. (B) The 34 DMN regions segmented utilizing the Dosenbach atlas. (C) The flowchart depicting the methodology for calculating individual variability based on the functional connectivity between the DMN and other cerebral regions. DMN default mode network, Sub subject, RSFC resting-state functional connectivity, MDD major depressive disorder, HC healthy controls, Corr correlation, ROI region of interest, FC functional connectivity, IVFC individual variability of functional connectivity.