Fig. 1 | Scientific Reports

Fig. 1

From: Molecular mechanisms and therapeutic targets in glioblastoma multiforme: network and single-cell analyses

Fig. 1

Identification of module genes in glioma and non-tumorous samples using weighted gene coexpression network analysis (WGCNA). (A) Cluster dendrogram of the coexpression network modules. (B) A coexpression network was visualized via heatmaps. (C) Module-trait correlation heatmap. (D-E) Scatter plots of module membership (MM) values vs. gene significance (GS) values for the turquoise (D) and blue modules (E). Genes with MM values > 0.8 and GS values > 0.2 are colored. (F-I) Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses of the hub genes in the turquoise (F-G) and blue (H-I) modules. Hub genes are defined as those with MM values > 0.8 and GS values > 0.2.

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