Fig. 3
Analysis of the blue module subnetwork genes in glioma and immune infiltration. (A) Heatmap of genes from the blue module subnetworks in The Cancer Genome Atlas-Low-Grade Glioma (TCGA-LGG) and TCGA-glioblastoma multiforme (GBM) datasets. (B–C) Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses of genes from the blue module subnetworks. (D) Differential proportions of 22 immune cell types between the blue module subnetwork low-score and blue module subnetwork high-score groups were determined via CIBERSORT. (E) Box plot displaying the differential infiltration levels of 22 immune cell types between the blue module subnetwork low-score and blue module subnetwork high-score groups. (F) Correlations of 22 immune cell types with blue module subnetwork genes.
