Fig. 4 | Scientific Reports

Fig. 4

From: Vaginal microbiota transplantation alleviates vaginal atrophy in ovariectomized mice

Fig. 4

Compositional analysis and functional prediction of VM in different groups of mice. (A) UPGMA cluster analysis based on Unifrac weighted distance matrix. (B) Gammaproteobacteria (one-way ANOVA, F4, 25 = 12.35, P < 0.001). (C) Bacilli (one-way ANOVA, F4, 25 = 7.774, P = 0.0003). (D) Clostridia (one-way ANOVA, F4, 25 = 11.56, P < 0.0001). (E) Actinobacteria (one-way ANOVA, F4, 25 = 13.88, P < 0.001). (F) Bacteroidia (one-way ANOVA, F4, 25 = 3.028, P = 0.0364). (G) Differences in VM between groups at the genus level STAMP. (H) Relative abundance bar chart displaying COG function for each sample. (I) COG function differences be-tween groups: function unknown (one-way ANOVA, F4, 25 = 8.954, P < 0.0001). (J) COG function differences between groups: cell cycle control, cell division, chromosome partitioning (one-way ANOVA, F4, 25 = 11.05, P < 0.0001). (BF) The five most abundant species in each group of VM at the phylum level. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. ANOVA: analysis of variance. Only differences with P value less than 0.05 are shown.

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