Fig. 6

Differences in the abundance of VM metabolites between groups and functional analysis. (A) N-acetyl-d-galactosamine; (B) lamivudine; (C) urocanic acid; (D) octadecanoic acid; (E) 1-palmitoyl-2-linoleoyl-rac glycerol; (F) arachidoyl ethanolamide; (G) hydrocortisone 21-acetate; (H) bufalin; (I) 1,2-dioleoyl-sn-glycero-3-glycol; (J) Metabolic pathway enrichment is represented by bubbles in the graph. Each bubble corresponds to a metabolic pathway, with the horizontal coordinate indicating the p-value of the enrichment analysis. The size of each bubble indicates the number of different metabolites enriched in the pathway, with larger bubbles indicating a greater number of metabolites. The color of each bubble represents the corresponding rich factor of each pathway, with redder colors indicating higher values. (K) The figure displays the results of the MetPA enrichment analysis. Each circle represents a metabolic pathway, with the horizontal coordinate indicating the degree of pathway impact. The size of each circle corresponds to the pathway impact, with larger circles indicating greater impact values. The vertical coordinate represents the negative logarithm of the P-value obtained from the pathway enrichment analysis. The color of the circle changes from blue to red as the negative logarithm of the P-value decreases, indicating a higher level of significance for the pathway change. The color change of the point from blue to red indicates a positive correlation with the negative logarithm of the P value of the pathway change. A redder color indicates a more significant enrichment of the pathway. The figure shows the top 5 pathways with smaller P values and their respective names.