Fig. 5 | Scientific Reports

Fig. 5

From: Spatial transcriptomics of the epipharynx in long COVID identifies SARS-CoV-2 signalling pathways and the therapeutic potential of epipharyngeal abrasive therapy

Fig. 5

Spatial gene expression and histological analysis of the epipharyngeal epithelium before and after treatment in patients with long COVID. (a) The upper panels show the spatial gene expression analysis of the epipharyngeal tissue in long COVID patients pre-EAT and post-EAT. The epithelium pre-EAT showed a higher proportion of Cluster 7, whereas the epithelium post-EAT showed higher proportions of Clusters 12 and 9, each of which is highlighted in yellow in the tissue. The lower panels display H&E staining results with magnified views of the epithelium, highlighting structural changes before and after treatment. (b) Bar graph of the enriched terms in the upregulated DEGs in Clusters 12 and 9, representing the post-EAT epithelium.

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