Table 2 Predicted discontinuous epitopes of B-cells as determined by three different analytical tools.

From: Computationally designed multi-epitope vaccine construct targeting the SARS-CoV-2 spike protein elicits robust immune responses in silico

Conformational epitopes

Epitope region

Length

PI score

B-Ep1

I326, V327, K529, S530, T531, N532

6

0.91

B-Ep2

L455, K458, S459, Q474, A475, G476, S477, T478, P479, C480, N481, G482, V483, E484, G485, F486, N487, C488, Y489, F490, P491

21

0.70

B-Ep3

R403, G404, D405, N437, N439, N440, L441, S443, K444, V445, G446, G447, N448, Y449, N450, Y451, G496, F497, Q498, P499, T500, N501, G502, V503, G504, Y505, Q506, P507

28

0.67

B-Ep4

P330, T333, V362, A363, V382, L390, C391, A522, T523, C525, G526, P527

12

0.65

B-Ep5

A411, P412, G413, Q414, T415, P426, D427, D428

8

0.54

  1. B-Ep: B-cell epitope.
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