Fig. 2 | Scientific Reports

Fig. 2

From: Diffusion MRI with double diffusion encoding and variable mixing times disentangles water exchange from transient kurtosis

Fig. 2

Principle of tMGE. The SDE measurement gives the total kurtosis including all contributions. DDE measurements at any mixing time reduce the kurtosis by half the transient value plus exchange-driven attenuation. The DDE points allow estimation of \(K_{0}\) and \(k\) which in turn allow prediction of the SDE measurement under the assumption of zero transient kurtosis. Any deviation between the predicted and observed SDE kurtoses manifests as transient kurtosis.

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