Fig. 3

(a) and (b) represent snapshot showing interaction of K-loop with DNA in hTopoII and ScTopo II, respectively. (c) and (d) show distance map of K-loop sensing/interaction with DNA in hTopoII and ScTopo II, respectively. Here K-loop is in licorice with blue colour and closest nucleotides are in licorice, grey colour. Similarly, in case of hTopoII, K-loop is presented in blue licorice.