Fig. 4

(a) Potential inhibitor binding areas (hotspots) in the middle region of K-loop and helix like region (HLR) of ScTopoII, (b) inter chain HLR-HLR and (c) interaction between helix supported loop region and helix like region.

(a) Potential inhibitor binding areas (hotspots) in the middle region of K-loop and helix like region (HLR) of ScTopoII, (b) inter chain HLR-HLR and (c) interaction between helix supported loop region and helix like region.