Table 5 Predictive factors for avoiding axillary lymph node dissection in univariate and multivariate analysis.

From: Achieving treatment goals in older breast cancer patients receiving neoadjuvant chemotherapy

 

Univariate Analysis

HR (%95CI)

p-value

Multivariate Analysis

HR (%95 CI)

p-value

Age < 65y vs. > 65y

0.88 (0.52–1.49)

0.653

  

HER2-positive vs. HER2 negative

1.92 (1.32–2.78)

0.001

1.73(1.13–2.64)

0.011

Ki67>%30 vs. Ki67<%30

1.57 (1.07–2.30)

0.019

1.46(0.95–2.24)

0.082

Grade 3 vs. Grade 1–2

1.31 (0.92–1.86)

0.133

  

ER negative vs. ER positive

1.51(1.03–2.20)

0.033

1.3(0.73 − 2.30)

0.363

PR negative vs. PR positive

1.72(1.21–2.45)

0.002

1.76(1.04–2.99)

0.033

cT1-2 vs. cT3-4

1.40(0.96–2.04)

0.073

  

cN0-1 vs. cN2-3

2.09(1.46–2.99)

0.000

2.26(1.51–3.37)

0.000

ddAC vs. AC

2.93 (1.93–4.46)

0.000

2.91 (1.86–4.57)

0.000

  1. ER: estrogen receptor, PR: progesterone receptor, dd: dose-dense A: Adriamycin C: cyclophosphamide.