Table 5 Predictive factors for avoiding axillary lymph node dissection in univariate and multivariate analysis.
From: Achieving treatment goals in older breast cancer patients receiving neoadjuvant chemotherapy
Univariate Analysis HR (%95CI) | p-value | Multivariate Analysis HR (%95 CI) | p-value | |
|---|---|---|---|---|
Age < 65y vs. > 65y | 0.88 (0.52–1.49) | 0.653 | ||
HER2-positive vs. HER2 negative | 1.92 (1.32–2.78) | 0.001 | 1.73(1.13–2.64) | 0.011 |
Ki67>%30 vs. Ki67<%30 | 1.57 (1.07–2.30) | 0.019 | 1.46(0.95–2.24) | 0.082 |
Grade 3 vs. Grade 1–2 | 1.31 (0.92–1.86) | 0.133 | ||
ER negative vs. ER positive | 1.51(1.03–2.20) | 0.033 | 1.3(0.73 − 2.30) | 0.363 |
PR negative vs. PR positive | 1.72(1.21–2.45) | 0.002 | 1.76(1.04–2.99) | 0.033 |
cT1-2 vs. cT3-4 | 1.40(0.96–2.04) | 0.073 | ||
cN0-1 vs. cN2-3 | 2.09(1.46–2.99) | 0.000 | 2.26(1.51–3.37) | 0.000 |
ddAC vs. AC | 2.93 (1.93–4.46) | 0.000 | 2.91 (1.86–4.57) | 0.000 |