Table 2 Multivariate Cox proportional hazards model for OS and PFS.

From: Beta-adrenergic receptor blockers improve survival in patients with advanced non-small cell lung cancer combined with hypertension undergoing radiotherapy

Variables

OS

PFS

HR

95%CI

p value

HR

95%CI

p value

KPS

      

< 80

0.76

0.51–1.23

0.23

0.64

0.23–1.04

0.06

≥ 80

Ref

  

Ref

  

Clinical stage

      

III A

Ref

  

Ref

  

III B

0.97

0.67–1.44

0.22

1.42

0.89–1.87

0.57

Hypertension risk

      

Low risk group

Ref

  

Ref

  

Middle risk group

1.01

0.86–1.33

0.85

1.32

0.88–1.64

0.45

High risk group

1.15

0.75–1.31

0.63

1.25

0.85–1.44

0.33

Very high risk group

1.24

0.65–1.29

0.42

1.31

0.63–1.84

0.22

Use of β-blockers

      

No

Ref

     

Yes

0.71

0.33–0.91

0.01*

0.64

0.39–0.96

0.03*

  1. OS: overall survival, PFS: progression-free survival, HR: hazard ratio, CI: confidence interval, KPS: KarnofskyPerformance Status. *p value is significant.