Table 5 Regression coefficients from multiple regression model for time to wean success (n = 1358).

From: The COVIDTrach prospective cohort study on outcomes in 1982 tracheostomised COVID-19 patients during the first and second UK pandemic waves

Predictor

Category

Coefficient (95% CI)

P-value

Age

< 30

0

 < 0.001

30–49

0.13 (− 0.16 to 0.42)

 

50–69

0.25 (− 0.03 to 0.54)

 

70 + 

0.46 (0.17 to 0.76)

 

Sex

 

 − 0.146 (− 0.224 to − 0.069)

 < 0.001

Anticoagulant

 

0.112 (0.037 to 0.188)

0.004

Inotropic support

 

0.101 (0.021 to 0.180)

0.013

Use of NIV

 

0.175 (0.101 to 0.249)

 < 0.001

Days of ventilation before tracheostomy

≤ 7

0

0.004

8–14

0.13 (0.05 to 0.21)

 

> 14

0.21 (− 0.11 to 0.52)

 

FiO2 requirement

< 30

0

 < 0.001

30–39

0.15 (0.04 to 0.27)

 

40–49

0.24 (0.12 to 0.36)

 

50 + 

0.37 (0.23 to 0.51)

 

PO2

< 8

0

0.015

8–10

 − 0.10 (− 0.25 to 0.06)

 

10.01–12

 − 0.15 (− 0.31 to 0.01)

 

12.1–14

 − 0.24 (− 0.42 to − 0.05)

 

> 14

 − 0.30 (− 0.51 to − 0.08)

 

PEEP setting

< 6

0

0.001

6–7.9

0.06 (− 0.06 to 0.18)

 

8–9.9

0.16 (0.05 to 0.26)

 

10 + 

0.21 (0.09 to 0.32)

 

Method of tracheostomy (baseline category is ‘open’ tracheostomy)

 

0.105 (0.030 to 0.181)

0.006