Fig. 1
Synthesis of amino acid conjugates of mono-carbonyl curcumin H1-H6. Reagents and conditions: (a) (BOC)2O, triethylamine, acetone and water, 0–40 ℃, 4 h; (b) EDCI, DMAP, N2 protection, CH2Cl2, 7–12 h; (c) 2 M HCl in CH3OH solution, 0℃, 2–3 h.
Fig. 1 | Scientific Reports
