Table 1 Docking results (Kcal/mol) of SP models of H1-H6 with AKT protein (3O96) and FOXO1 protein(6AEJ).
Conjugates | AKT protein | Conjugates | FOXO1 protein |
|---|---|---|---|
H1 | −10.486 | H1 | −8.771 |
H5 | −10.198 | H2 | −8.293 |
H2 | −9.947 | H5 | −8.291 |
3O96 ligand | −9.363 | 6AEJ ligand | −8.215 |
H3 | −9.182 | H3 | −8.192 |
H4 | −8.917 | Mono-carbonyl curcumin | −8.19 |
Mono-carbonyl curcumin | −7.724 | Curcumin | −8.089 |
Curcumin | −7.369 | H4 | −8.081 |
H6 | −7.301 | H6 | −6.247 |
