Table 3 The inhibitory zone (mm), MIC (μg/mL), and MBC (μg/mL) of ROLEO.

From: In vitro and in silico pharmacological effects of Rosmarinus officinalis leaf methanolic extracts and essential oils

Bacterium/dilution

Positive control

400 μg/mL

200 μg/mL

100 μg/mL

50 μg/mL

MIC (μg/mL)

MBC (μg/mL)

S. aureus

27 ± 0.61

25 ± 2.55

21 ± 2.21*

18 ± 1.48*

14 ± 2.34*

4.68 ± 2.21

6.25 ± 0.00

S. epidermidis

25 ± 1.57

22 ± 1.41*

16 ± 2.84*

14 ± 2.36*

11 ± 1.12*

6.25 ± 0.00

12.50 ± 0.00

E. faecalis

24 ± 2.42

22 ± 1.35*

18 ± 1.34*

15 ± 1.25*

11 ± 2.24*

6.25 ± 0.00

12.50 ± 0.00

E. coli

29 ± 1.12

20 ± 2.61*

17 ± 1.57*

15 ± 1.33*

8 ± 0.29*

25 ± 0.00

50 ± 0.00

K. pneumoniae

25 ± 1.33

23 ± 1.34*

20 ± 1.32*

16 ± 1.96*

10 ± 1.73*

12.50 ± 0.00

25 ± 0.00

P. aeruginosa

26 ± 2.68

19 ± 1.38*

16 ± 1.96*

13 ± 1.14*

9 ± 1.30*

12.50 ± 0.00

25 ± 0.00

  1. The reported values represent the mean of three separate experiments, with the standard deviation (SD) indicating the variability within the data. The asterisk (*) denotes statistical significance lower than positive control (Chloramphenicol, 25 µg/ml) with P < 0.01.
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