Table 4 The inhibitory zone (mm), MIC (μg/mL), and MBC (μg/mL) of ROLME.

From: In vitro and in silico pharmacological effects of Rosmarinus officinalis leaf methanolic extracts and essential oils

Bacterium/dilution

Positive control

400 μg/mL

200 μg/mL

100 μg/mL

50 μg/mL

MIC (μg/mL)

MBC (μg/mL)

S. aureus

27 ± 0.61

17 ± 2.71*

14 ± 0.34*

11 ± 2.35*

6 ± 1.65*

25 ± 0.00

50.00 ± 0.00

S. epidermidis

25 ± 1.57

19 ± 0.93*

14 ± 1.42*

11 ± 1.93*

7 ± 1.71*

12.50 ± 0.00

25.00 ± 0.00

E. faecalis

24 ± 2.42

18 ± 1.32*

16 ± 1.96*

13 ± 1.74*

8 ± 0.38*

25 ± 0.00

50.00 ± 0.00

E. coli

29 ± 1.12

22 ± 0.85*

17 ± 1.24*

13 ± 1.43*

11 ± 1.32*

12.50 ± 0.00

50.00 ± 0.00

K. pneumoniae

25 ± 1.33

20 ± 3.92*

17 ± 0.89*

13 ± 1.83*

9 ± 0.22*

25 ± 0.00

50.00 ± 0.00

P. aeruginosa

26 ± 2.68

19 ± 2.59*

16 ± 1.33*

12 ± 2.36*

10 ± 1.62*

12.50 ± 0.00

25.00 ± 0.00

  1. The reported values are shown in triplicate as mean ± SD. The results demonstrate a statistically significant decrease from the positive control (25 µg/ml of chloramphenicol), indicated by (* = P < 0.01).
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