Fig. 7

Analysis of Potential Mechanisms by Which BHMT Affects Tumor Prognosis. Utilizing BHMT associated genes, GO (a) and KEGG (b) enrichment analyses were conducted using BHMT-associated genes. In panel A, GO enrichment includes three categories: Biological Process (BP), Cellular Component (CC), and Molecular Function (MF). Furthermore, association analysis between BHMT and EHHADH (c), as well as ACSL1 (d) were applied. Based on tissue microarray of paraffin-embedded samples from 96 clinical HCC patients, immunohistochemistry about EHHADH (e) and ACSL1 (f) was performed to investigate their expression in BHMT positive and negative HCC tissues. The scale bar represents 100 μm.