Fig. 5
From: Plakoglobin does not participate in endothelial barrier stabilization mediated by cAMP

Localization pattern of junctional and junctional-related proteins after cAMP elevation in WT and PG-KO cells. (a) Representative immunostaining for VE-cadherin, β-catenin, ZO-1 and cortactin in confluent monolayers of WT and PG-KO cells either subjected to Vehicle or F/R; N ≥ 3 (b) Bell-shaped curve depicted the pixel intensity of the specific signals across cell-cell contact for VE-cadherin, β-catenin and ZO-1 in treated cells with and without PG; N ≥ 3. The “*” for VE-cadherin and β-catenin, symbolized the significant difference in the pixel intensity detected between vehicle and F/R -treated WT monolayers; N ≥ 3. * p ≤ 0,05.