Fig. 7
From: Plakoglobin does not participate in endothelial barrier stabilization mediated by cAMP
Importance of PG Ser665 phosphorylation site for cAMP-mediated endothelial barrier stability. (a) Western blot analysis, in WT and PGSer665Ala mutant cells, with specific antibody recognizing the phosphorylated form of PG at position Ser665, i.e. PGSer665. Cell monolayers were either treated or not with F/R; α-tubulin was used for equal loading; N = 4. (b) TEER-based barrier integrity measurements in PgSer665Ala confluent monolayers exposed to Vehicle or F/R-treatment; N = 6. Data are presented as mean ± SEM.
