Fig. 6
From: Anticancer drugs targeting topoisomerase II for antifungal treatment
Assessment of ROS generation in Saccharomyces cerevisiae following idarubicin treatment via flow cytometry. DMSO and H2O2 were used as negative and positive controls, respectively. (A) Representative histograms demonstrate ROS induction across different treatment conditions; (B) Quantitative analysis of ROS levels. Error bars represent the SEM from three independent experiments (n = 3). Statistical significance is indicated as **p < 0.001, ****p < 0.00001 compared to the vehicle control (two-way ANOVA with Dunnett’s post hoc test).
