Fig. 4
From: A computational framework for detecting inter-tissue gene-expression coordination changes with aging
Differential Connectivity (MDC) of 8 selected modules. The topological overlap matrix (TOM) plots correspond to young modules (the upper off-diagonal panel) and the old modules (the lower off-diagonal panel). The rows and columns represent the same set of the most variably expressed genes in each of the three tissues and states. In each panel MDC and FDR estimate are specified in parenthesis as well as the enriched GO biological process. Six modules (four cross-tissue (CT) modules) have a gain of connectivity (GOC) and two modules (one cross-tissue (CT) module) have a loss of connectivity (LOC) between the young and old cohorts.
