Fig. 4
From: Extracorporeal shock waves effectively suppress colorectal cancer proliferation and growth
60 mJ ESV induces apoptosis and ferroptosis in CRC cells. A Gene set enrichment analysis plots for apoptosis. NES, normalized enrichment score; Black bars represent genes contained within the specific pathway ranked from positively expressed (left) to negatively expressed (right) based on log twofold change (60 mJ ESV vs. CON). B Western blot analysis of cleaved-PARP and cleaved-caspase3. C cleaved-PARP and cleaved-caspase3 densitometry relative to β-actin. D cleaved-caspase3 staining (Scale: 100 μm). E The relative mRNA levels of AKR1C1 and COX2 measured by real-time PCR. F Western blot analysis of AKR1C1 and COX2. G AKR1C1 and COX2 densitometry relative to β-actin. *p < 0.05, ***p < 0.001.
