Table 1 Baseline characteristics of patients with SFTS.

From: Dynamic biomarkers and Cox regression with time-dependent covariate for mortality prediction in severe fever with thrombocytopenia syndrome

Characteristics

Overall (n = 440)

Survivors (n = 364)

Non-survivor (n = 76)

p-value

Demographics

Age (year)

66.94 (13.20)

65.62 (13.57)

73.28 (8.89)

< 0.001

Gender, n (%)

  Male

  Female

212 (48.2)

228 (51.8)

177 (48.6)

187 (51.4)

35 (46.1)

41 (53.9)

0.778

Height (cm)

162.22 (9.12)

162.14 (9.29)

162.59 (8.32)

0.714

Weight (kg)

61.50 (13.16)

61.36 (13.19)

62.19 (13.11)

0.630

Comorbidities

    

Diabetes, n (%)

77 (17.5)

55 (15.1)

22 (28.9)

0.006

Hypertension, n (%)

164 (37.3)

127 (34.9)

37 (48.7)

0.033

Duration

Onset of illness to admission (days)

4.78 (2.77)

4.79 (2.78)

4.74 (2.77)

0.877

Onset of illness to discharge or death (days)

15.40 (9.25)

16.46 (9.58)

10.29 (5.00)

< 0.001

Hospitalization (days)

11.61 (9.03)

12.67 (9.45)

6.55 (3.73)

< 0.001

Laboratory finding

WBC count (×10³/µL)

2.37 (1.98)

2.36 (1.89)

2.43 (2.42)

0.780

Platelet count (×10³/µL)

73.31 (39.30)

75.82 (40.02)

60.83 (33.06)

0.003

Neutrophil count (×10³/µL)

1.45 (1.50)

1.42 (1.43)

1.57 (1.82)

0.466

Lymphocyte count (×10³/µL)

0.69 (0.59)

0.70 (0.59)

0.62 (0.54)

0.280

Monocyte count (×10³/µL)

0.16 (0.18)

0.17 (0.18)

0.12 (0.14)

0.026

Hemoglobin (g/dL)

13.52 (1.91)

13.54 (1.93)

13.38 (1.80)

0.491

Hematocrit (%)

39.75 (6.09)

39.95 (5.93)

38.76 (6.77)

0.132

Sodium (mmol/L)

135.34 (4.36)

135.30 (4.23)

135.58 (4.99)

0.615

Potassium (mmol/L)

3.95 (0.62)

3.93 (0.61)

4.03 (0.66)

0.235

AST (IU/L)

291.23 (402.11)

236.84 (306.97)

560.94 (643.12)

< 0.001

ALT (IU/L)

111.66 (138.77)

102.75 (132.77)

155.85 (159.12)

0.003

LDH (IU/L)

1048.04 (1083.16)

884.82 (769.15)

1873.88 (1827.72)

< 0.001

Total Bilirubin (mg/dL)

0.46 (0.37)

0.44 (0.34)

0.55 (0.52)

0.022

Total Protein (g/dL)

6.15 (0.73)

6.22 (0.70)

5.79 (0.79)

< 0.001

Albumin (g/dL)

3.57 (0.52)

3.63 (0.49)

3.27 (0.58)

< 0.001

BUN (mg/dL)

21.24 (13.99)

19.80 (12.51)

28.49 (18.27)

< 0.001

Creatinine (mg/dL)

1.06 (0.64)

1.01 (0.59)

1.29 (0.80)

0.001

CRP (mg/L)

66.84 (44.93)

65.14 (41.60)

75.44 (58.58)

0.089

Troponin-I (ng/mL)

4.99 (17.77)

4.40 (18.18)

8.19 (15.07)

0.117

CK-MB (ng/mL)

0.73 (4.21)

0.76 (4.68)

0.63 (1.32)

0.883

PT (sec)

8.91 (15.24)

7.47 (12.71)

14.33 (21.64)

0.003

aPTT (sec)

12.31 (1.67)

12.08 (1.13)

13.43 (2.96)

< 0.001

eGFR (mL/min/1.73 m²)

44.76 (16.09)

42.13 (10.65)

57.77 (28.05)

< 0.001

pH

7.18 (0.62)

7.15 (0.66)

7.34 (0.34)

0.024

PaCO2 (mmHg)

36.09 (8.09)

36.87 (7.62)

33.10 (9.17)

0.001

PaO2 (mmHg)

56.38 (30.64)

54.67 (30.09)

63.00 (32.06)

0.052

  1. Data are presented as mean (standard deviation) for continuous variables and count (percentage) for categorical variables. Laboratory findings and variable index are evaluated among available data.