Fig. 1

Differential expression of IRF Family members in LUAD. The expression box plots show that IRF3/4/6/7/9 were upregulated in LUAD tissues, while IRF1/2/8 were downregulated (A, C). A similar pattern in expression dynamics is observable in a matched sample set comprising 57 pairs of tumor and adjacent non-tumor tissues (B, D). Statistical comparisons were made using a t-test, ***P-value < 0.001, **P-value < 0.01, *P-value < 0.05. OS was analyzed using the Kaplan–Meier Plotter method, *P < 0.05.