Fig. 4 | Scientific Reports

Fig. 4

From: Effects of whole brain proton irradiation at conventional or ultra-high dose rate (FLASH), in adult male Sprague Dawley rats

Fig. 4

Acoustic startle response (a) and tactile startle response (b) of irradiated and Sham rats. The FLASH-95 rats had increased ASR compared with the Sham rats, whereas the CV and FLASH-60 rats did not differ from Sham rats. There were no differences between the CV rats and the FLASH rats (a). All irradiated groups had increased TSR relative to the Sham group, but there were no differences between the CV and FLASH groups (b). Startle responses were analyed by Dunnett’s and an irradiation × block (repeated) ANOVA for each pulse. *p < 0.05, **p < 0.01, ***p < 0.001. Because of nonresponses group sizes were for ASR: Sham = 18, FLASH-95 = 17, FLASH-60 = 16, and CV = 20 and for TSR: Sham = 20, FLASH-95 = 16, FLASH-60 = 15, and CV = 20.

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