Table 2 Effect of infection with HPV subtypes on maternal outcomes.

From: The distribution and the relationship of HPV subtypes infection with pregnancy outcomes

Variables

HPV group

N

Event, n(%)

Crude

Adjusted

OR (95%CI)

P value

OR (95%CI)

P value

GDM

Control

5690

1294 (22.7)

1(Ref)

 

1(Ref)

 

I

216

49 (22.7)

1.00 (0.72 ~ 1.38)

0.984

1.03 (0.74 ~ 1.44)

0.849

II

655

123 (18.8)

0.79 (0.64 ~ 0.96)

0.021

0.82 (0.66 ~ 1.01)

0.060

III

414

87 (21.0)

0.90(0.71 ~ 1.15)

0.418

0.89 (0.70 ~ 1.15)

0.384

IV

135

27 (20.0)

0.85 (0.55 ~ 1.30)

0.453

0.92 (0.59 ~ 1.42)

0.704

HPV infection

1420

286 (20.1)

0.86 (0.74 ~ 0.99)

0.035

0.88 (0.76 ~ 1.02)

0.092

HDCP

Control

5690

187 (3.3)

1(Ref)

 

1(Ref)

 

I

216

11 (5.1)

1.58 (0.85 ~ 2.95)

0.151

1.61 (0.86 ~ 3.01)

0.135

II

655

28 (4.3)

1.31 (0.88 ~ 1.97)

0.187

1.36 (0.91 ~ 2.05)

0.138

III

414

13 (3.1)

0.95 (0.54 ~ 1.69)

0.872

0.95 (0.54 ~ 1.68)

0.860

IV

135

11 (8.1)

2.61 (1.39 ~ 4.92)

0.003*

2.73 (1.44 ~ 5.15)

0.002*

HPV infection

1420

63 (4.4)

1.37 (1.02 ~ 1.83)

0.036

1.40 (1.04 ~ 1.87)

0.025*

PPROM

Control

5690

1448 (25.4)

1(Ref)

 

1(Ref)

 

I

216

58 (26.9)

1.08 (0.79 ~ 1.46)

0.642

1.06 (0.78 ~ 1.45)

0.706

II

655

200 (30.5)

1.29 (1.08 ~ 1.54)

0.005*

1.29 (1.08 ~ 1.55)

0.005*

III

414

94 (22.7)

0.86 (0.68 ~ 1.09)

0.215

0.86 (0.67 ~ 1.09)

0.203

IV

135

35 (25.9)

1.03 (0.69 ~ 1.51)

0.900

1.01 (0.68 ~ 1.49)

0.977

HPV infection

1420

387 (27.3)

1.10 (0.96 ~ 1.25)

0.164

1.09 (0.96 ~ 1.25)

0.186

Placental abruption

Control

5690

145 (2.5)

1(Ref)

 

1(Ref)

 

I

216

3 (1.4)

0.54 (0.17 ~ 1.70)

0.292

0.53 (0.17 ~ 1.70)

0.289

II

655

11 (1.7)

0.65 (0.35 ~ 1.21)

0.177

0.64 (0.34 ~ 1.20)

0.162

III

414

12 (2.9)

1.14 (0.63 ~ 2.07)

0.664

1.22 (0.67 ~ 2.22)

0.521

IV

135

3 (2.2)

0.87 (0.27 ~ 2.76)

0.812

0.96 (0.30 ~ 3.07)

0.951

HPV infection

1420

29 (2)

0.80 (0.53 ~ 1.19)

0.270

0.81 (0.54 ~ 1.22)

0.321

Postpartum hemorrhage

Control

5690

471 (8.3)

1(Ref)

 

1(Ref)

 

I

216

18 (8.3)

1.01 (0.62 ~ 1.65)

0.977

1.04 (0.63 ~ 1.70)

0.887

II

655

50 (7.6)

0.92 (0.68 ~ 1.24)

0.570

0.95 (0.70 ~ 1.29)

0.760

III

414

38 (9.2)

1.12 (0.79 ~ 1.58)

0.522

1.11 (0.78 ~ 1.57)

0.567

IV

135

9 (6.7)

0.79 (0.40 ~ 1.57)

0.502

0.84 (0.42 ~ 1.67)

0.618

HPV infection

1420

115 (8.1)

0.98 (0.79 ~ 1.21)

0.826

1.00(0.81 ~ 1.24)

0.991

Cesarean delivery

Control

5690

2029 (35.7)

1(Ref)

 

1(Ref)

 

I

216

77 (35.6)

1.00 (0.75 ~ 1.33)

0.997

1.02 (0.76 ~ 1.38)

0.875

II

655

257 (39.2)

1.17 (0.99 ~ 1.38)

0.071

1.25 (1.06 ~ 1.49)

0.010*

III

414

154 (37.2)

1.07 (0.87 ~ 1.31)

0.528

1.07 (0.86 ~ 1.33)

0.526

IV

135

59 (43.7)

1.40 (0.99 ~ 1.98)

0.055

1.59 (1.11 ~ 2.27)

0.011*

HPV infection

1420

547 (38.5)

1.13 (1.00 ~ 1.27)

0.045

1.19 (1.05 ~ 1.35)

0.006*

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