Fig. 5 | Scientific Reports

Fig. 5

From: Intratracheal Candida administration induced lung dysbiosis, activated neutrophils, and worsened lung hemorrhage in pristane-induced lupus mice

Fig. 5

Characteristics of tissue-resident macrophages (peritoneal macrophages) of mice from control, pristane injection, Candida administration (Candida), and pristane plus Candida (Pris + Can) as indicated by the biomarkers of M1 pro-inflammatory macrophages, including the expression of iNOS and IL-1β (using PCR) with CD80 and CD86 (flow cytometry), (A–D), M2 anti-inflammatory macrophages using Arg-1, Fizz-1, and TGF-β (PCR) with CD206 and CD163 (flow cytometry), (E–I), and expression of inflammatory genes (TNF-α, IL-6, IL-10, TLR-4, Dectin-1, and NF-κB) (J–O) are demonstrated (n = 5 /group).

Back to article page