Fig. 2 | Scientific Reports

Fig. 2

From: The effective-compound compatibility of JHF inhibits fibroblast activation in pulmonary fibrosis by enhancing PINK1/PARK2-mediated mitophagy

Fig. 2

ECC-JHF suppresses oxidative stress and enhances mitochondrial autophagy in lung tissue. (A) The activity of T-SOD. (B) The content of MDA. (C) Immunohistochemical analysis of Nrf2, HO-1, and IHS score assessment (magnification, × 200). (D) Transmission electron microscopy: the red arrows indicate autophagosomes and the blue indicate mitochondria (magnification, × 30000). (E) Immunohistochemical analysis of PINK1, Park2, p62 and LC3B and IHS score assessment (magnification, × 200). All data were expressed as mean ± SE (n = 6). *p < 0.05, **p < 0.01, vs. control group. #p < 0.05, ##p < 0.01, vs. BLM group.

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