Fig. 3 | Scientific Reports

Fig. 3

From: Optimizing UK biobank cloud-based research analysis platform to fine-map coronary artery disease loci in whole genome sequencing data

Fig. 3

Miami Plot of Chromosome 9 for single-SNV Logistic Regression (Top) and VariantSpark (Bottom). The locus 9p21.3 reached genome-wide significance in the logistic regression analysis and is the top association from VariantSpark. Note that the Gini score (bottom y-axis) is used to measure variable importance and while it is analogous to the traditional P-values of logistic regression to rank associations relative to other associations, it does not include multiple testing and does not have guiding significance thresholds.

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