Fig. 7

Remimazolam ameliorated LPS-induced morphology damage of primary hippocampal neurons. The transmission electron microscopy (TEM) images showed neuronal damage induced by LPS in the hippocampus CA1 region, which manifested as extensive vacuolar degeneration, chromatin margination, and cell shrinkage. Remimazolam improves these morphological changes. The scale bar represents 200Â nm.