Table 4 Statistics on virulence factors of Rothia nasimurium.

From: Virulence and resistance gene analysis of Rothia nasimurium by whole gene sequencing

Function

Virulence factors

Related genes

Adherence

porin

dnaK

GroEL

groEL2

GAPDH

plr/gapA

ClpC

clpC

Ent

entB

Nutritional/Metabolic factor

Copper exporter

ctpV

Glutamine synthesis

glnA1

Iron/manganese transport

sitA

Immune modulation

Capsule

pseF, rfbB, GBS_RS06585, gndA, galU

HspR

hspR

Exopolysaccharide

pgi

GPL locus

rmlA

Polysaccharide capsule

galE

AI-2

luxS

LOS

manB/yhxB

Pyrimidine biosynthesis

carB

Exoenzyme

Streptococcal enolase

eno

Zn +  + metalloprotease

zmp1

Invasion

LPS

LPG_RS03830

Petrobactin

GBAA_RS25985, GBAA_RS25990, GBAA_RS25995, GBAA_RS26000

SigA

sigA/rpoV

Regulation

ClpP

clpP

Dot/Icm T4SSsecreted effectors

lirB

EF-Tu

tufA

PanC/PanD

panC

PhoP

phoR, phoP

RelA

relA

Hemolysin

Cytolysin

cylR2

Stress survival

Proteasome-associated proteins

pafA

Nitrate reductase

narG, narH, narI

SigH

sigH

Effector delivery system

T6SS-II

clpV

Iron uptake

Mycobactin

mbtI

IdeR

ideR

SodA

sodA