Table 4 Statistics on virulence factors of Rothia nasimurium.
From: Virulence and resistance gene analysis of Rothia nasimurium by whole gene sequencing
Function | Virulence factors | Related genes |
|---|---|---|
Adherence | porin | dnaK |
GroEL | groEL2 | |
GAPDH | plr/gapA | |
ClpC | clpC | |
Ent | entB | |
Nutritional/Metabolic factor | Copper exporter | ctpV |
Glutamine synthesis | glnA1 | |
Iron/manganese transport | sitA | |
Immune modulation | Capsule | pseF, rfbB, GBS_RS06585, gndA, galU |
HspR | hspR | |
Exopolysaccharide | pgi | |
GPL locus | rmlA | |
Polysaccharide capsule | galE | |
AI-2 | luxS | |
LOS | manB/yhxB | |
Pyrimidine biosynthesis | carB | |
Exoenzyme | Streptococcal enolase | eno |
Zn + + metalloprotease | zmp1 | |
Invasion | LPS | LPG_RS03830 |
Petrobactin | GBAA_RS25985, GBAA_RS25990, GBAA_RS25995, GBAA_RS26000 | |
SigA | sigA/rpoV | |
Regulation | ClpP | clpP |
Dot/Icm T4SSsecreted effectors | lirB | |
EF-Tu | tufA | |
PanC/PanD | panC | |
PhoP | phoR, phoP | |
RelA | relA | |
Hemolysin | Cytolysin | cylR2 |
Stress survival | Proteasome-associated proteins | pafA |
Nitrate reductase | narG, narH, narI | |
SigH | sigH | |
Effector delivery system | T6SS-II | clpV |
Iron uptake | Mycobactin | mbtI |
IdeR | ideR | |
SodA | sodA |