Fig. 3
From: Design and bioactivity evaluation of a novel autotaxin inhibitor with anti-hepatic fibrosis effects
The properties of top-ranked pharmacophore model (Pharmacophore_01). Pharmacophore is a model based on the characteristic elements of pharmacodynamics. The pharmacodynamic characteristic elements are mainly divided into seven types, including: hydrogen bond donors, hydrogen bond acceptors, positive and negative charge centers, aromatic ring centers, hydrophobic groups, hydrophilic groups, and geometric conformational volume collisions. Pharmacophore features are color-coded: pale blue, hydrophobic feature; orange yellow, ring aromatic feature; purple, negative ionizable feature.
