Table 6 Mendelian randomization analysis results of gout on bone necrosis.

From: Exploring the association between systemic lupus erythematosus and osteonecrosis by Mendelian randomization analysis

Method

Estimate

Std Error

OR

95% CI

P-value

Simple median

− 0.069

0.166

0.933

0.674

1.292

0.676

Weighted median

− 0.067

0.160

0.935

0.684

1.279

0.675

Penalized weighted median

− 0.067

0.160

0.935

0.684

1.279

0.675

IVW

− 0.087

0.114

0.917

0.733

1.147

0.449

Penalized IVW

− 0.087

0.114

0.917

0.733

1.147

0.449

Robust IVW

− 0.076

0.102

0.927

0.759

1.132

0.458

Penalized robust IVW

− 0.076

0.102

0.927

0.759

1.132

0.458

MR-Egger

0.040

0.241

1.041

0.649

1.670

0.867

Penalized MR-Egger

0.040

0.241

1.041

0.649

1.670

0.867

Robust MR-Egger

0.096

0.229

1.101

0.703

1.723

0.676

Penalized robust MR-Egger

0.096

0.229

1.101

0.703

1.723

0.676