Table 6 Univariate and multivariate COX regression analysis for CSS.

Age at diagnosis

<60 years

Ref.

-

Ref.

-

≥60 years

2.964(1.677–5.238)

<0.001

2.008(1.07–3.767)

0.003

Sex

Male

Ref.

-

-

-

Female

0.79(0.474–1.314)

0.363

-

-

Year of diagnosis

2010–2015

Ref.

-

-

-

2016–2021

0.677(0.407–1.125)

0.132

-

-

Marital status at diagnosis

Single (never married)

Ref.

-

Ref

-

Married (including common law)

2.879(1.251–6.625)

0.013

2.285(0.964–5.416)

0.061

Divorced

4.805(1.838–12.562)

0.001

3.688(1.352–10.061)

0.011

Widowed

8.268(2.843–24.043)

<0.001

4.874(1.566–15.169)

0.006

Race and Ethnicity

Hispanic (all races)

Ref.

-

-

-

Non-Hispanic White

0.819(0.412–1.628)

0.568

-

-

Non-Hispanic Black

0(0–0)

0.977

-

-

Non-Hispanic Asian or Pacific Islander

0.78(0.213–2.854)

0.708

-

-

Non-Hispanic American Indian/Alaska Native

1.46(0.185–11.508)

0.719

-

-

Median household income

<$75,000

Ref.

-

-

-

≥$75,000

0.807(0.487–1.338)

0.406

-

-

Chemotherapy

No/Unknown

Ref.

-

Ref.

-

Yes

0.418(0.202–0.862)

0.018

0.64(0.296–1.384)

0.257

PRCDA

Not PRCDA

Ref.

-

-

-

PRCDA

0.688(0.406–1.166)

0.165

-

-

Rural-Urban Continuum Code

Counties in metropolitan areas ge 1 million pop

Ref.

-

-

-

Counties in metropolitan areas of 250,000 to 1 million pop

1.635(0.913–2.929)

0.098

-

-

Counties in metropolitan areas of lt 250 thousand pop

0.662(0.255–1.721)

0.398

-

-

Nonmetropolitan counties adjacent to a metropolitan area

0.8(0.308–2.081)

0.648

-

-

Nonmetropolitan counties not adjacent to a metropolitan area

4.075(1.212–13.698)

0.023

-

-