Fig. 5

Correlation analysis of brain regions associated with FC abnormalities and clinical scales in patients with CRSsOD. (a) Correlation with PHQ-2 scores between left dorsolateral frontal cortex (dFC) and left mid-insula [47,96]. (b) Correlations with PHQ-2 scores between left dorsolateral frontal (dFC) and left parietal cortex [47,98]. (c) Correlations with LMS scores between right occipital and right post occipital regions [128,136] in patients with CRSsOD. (d) Correlation analysis of TDI scores between left dFC and left temporal [47,111] cortexes in patients with CRSsOD. (e) Correlations with TDI scores between left precentral gyrus and right occipital region [110,133]. CRSsOD chronic rhinosinusitis without olfactory dysfunction, CT computed tomography, dFC dorsolateral frontal cortex, FC functional connectivity, LMS sinus computed tomography Lund–Mackay score, PHQ-2 Patient Health Questionnaire-2, TDI threshold, discrimination, and identification in Sniffin Sticks tests.