Table 1 The impact of various catalyst concentrations and solvents on the ring opening of epichlorohydrin with aniline.
Entry | Solvents | Catalyst (mg) | Time (h) | Yield (%) |
|---|---|---|---|---|
1 | DCM | 10 | 24 | 24 |
2 | Toluene | 10 | 24 | 35 |
3 | CCl4 | 10 | 24 | 22 |
4 | Hexane | 10 | 24 | 20 |
5 | Acetonitrile | 10 | 24 | 38 |
6 | THF | 10 | 24 | 26 |
7 | Neat | 10 | 24 | 32 |
8 | Neat | 20 | 24 | 40 |
9 | Neat | 30 | 24 | 53 |
10 | Neat | Without catalyst | 24 | No reaction |
11 | Neat | Bare component | 24 | 20 |
12 | Neat | Carbonized | 24 | No reaction |