Table 5 Comparative study table for the synthesis methods of β-amino alcohols using various catalysts.
Catalyst | Reaction condition | Sustainability | %Yield of β amino alcohol | Refs. |
|---|---|---|---|---|
1 M HCl in ether | 0.5 mol % 1 M HCl in ether, toluene, rt, 3 h. | Metal free catalyst used | 96–91 | |
[Fe(BTC)] | epoxy (2.8 mmol), aniline (2.8 mmol), acetonitrile (4 mL), [Fe (BTC)] (50 mg), 40 °C, 16 h. | Recyclable Heterogenous catalyst | 93–49 | |
MCM type silica materials | MCM type mesoporous silica materials, epoxide (10 mmol), nucleophile (10 mmol), 6 h at 80 °C | Recyclable Heterogenous catalyst | 99–43 | |
Bi(PO4) | Bi(PO4) (10 mol%), epoxide (1.0 mmol), amine (1.0 mmol), microwave irradiation (900 W) | microwave irradiation | 88–24 | |
IONs(0.00249 mmol of Fe, 2.493 10–4 mol% of Fe) | RT, Neat, 5 h | Recyclable catalyst | 90 | |
Mesoporous Zr-Beta | Epoxide (5 mmol), amine (5 mmol), 25 mg catalyst, 308 K, 0.5 h | Mesoporous recyclable catalyst | 80 | |
CoFe@rGO | epoxide (1 mmol), Amine (1 mmol), Catalyst 20%, 12 h, 80 °C | Magnetic recyclable catalyst | 87 | |
nano Fe3O4 | RT, Neat, 20 h | Magnetic and neat condition | 83 | |
mesoporous TiO2 -Fe2O3 | Epoxide (1 mmol), amine (1 mmol), catalyst (20 mg), neat, 3 h, RT | Recyclable Porous nanomaterials | 96 | |
KPP | Epoxide (1 mmol), Amine (1 mmol), catalyst 30 mg, neat, 24 h, RT | Metal Free and fruit waste as recyclable catalyst | 53 | This work |
