Fig. 4 | Scientific Reports

Fig. 4

From: HIF-1 regulates mitochondrial function in bone marrow-derived macrophages but not in tissue-resident alveolar macrophages

Fig. 4

HIF-1α deletion results in increased mitochondrial gene and protein expression in BMDMs, but not TR-AMs. TR-AMs (A-B) and BMDMs (C-D) were cultured overnight (16 h) in the presence or absence of FG-4592 (25µM). (A, C) Western blot analysis of macrophage lysates to assess electron transport chain protein expression. (B, D) Heatmap of gene expression related to oxidative phosphorylation.

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