Table 1 Clinical features and 18F-FDG PET/CT findings of spinal intermediate bone tumors.

From: 18F-FDG PET/CT findings of intermediate bone tumors of the spine

Parameters

GCTB (N = 22)

Osteoblastoma (N = 11)

LCH (N = 10)

Epithelioid hemangioma (N = 6)

p

Age

36.3 ± 11.5

14.0 [10.0, 23.0]

26.0 [19.0, 39.0]

29.0 [31.0, 59.0]

0.006

Gender

 Man

15 (68.2%)

7 (63.6%)

6 (60.0%)

4 (66.7%)

0.976

 Woman

7 (31.8%)

4 (36.4%)

4 (40.0%)

2 (33.3%)

Location

 Cervical vertebra

4 (18.2%)

5 (45.4%)

4 (40.0%)

0 (0.0%)

0.215

 Thoracic vertebra

8 (36.4%)

1 (9.1%)

4 (40.0%)

5 (83.3%)

 Lumbar vertebra

1 (4.5%)

3 (27.3%)

2 (20.0%)

1 (16.7%)

 Sacral vertebrae

9 (40.9%)

2 (18.2%)

0 (0.0%)

0 (0.0%)

Epicenter of the lesion

 Vertebral body

16 (72.7%)

2 (18.2%)

9 (90.0%)

4 (66.7%)

0.002

 Posterior elements

6 (27.3%)

9 (81.8%)

1 (10.0%)

2 (33.3%)

 Maximum diameter

5.5 ± 1.6

2.4 ± 0.9

2.5 ± 0.7

3.4 ± 0.6

< 0.001

Cortical integrity

 Yes

4 (18.2%)

7 (63.6%)

3 (30.0%)

0 (0.0%)

0.014

 No

18 (81.8%)

4 (36.4%)

7 (70.0%)

6 (100.0%)

Sclerotic rim

 Yes

7 (31.8%)

8 (72.7%)

6 (60.0%)

0 (0.0%)

0.010

 No

15 (68.2%)

3 (27.3%)

4 (40.0%)

6 (60.0%)

Eccentric expansile osteolysis

 Yes

18 (81.8%)

10 (90.9%)

9 (90.0%)

6 (100.%)

0.656

 No

4 (18.2%)

1 (9.1%)

1 (10.0%)

0 (0.0%)

Residual bone crest/trabeculae or cacification

 Yes

18 (81.8%)

9 (81.8%)

6 (60.0%)

6 (100.0%)

0.172

 No

4 (18.2%)

2 (18.2%)

4 (40.0%)

0 (0.0%)

Vertebral compression

 Yes

14 (63.6%)

0 (0.0%)

2 (20.0%)

4 (66.7%)

< 0.001

 No

8 (36.4%)

11 (100.0%)

8 (80.0%)

2 (33.3%)

Soft tissue mass

 Yes

21 (95.5%)

11 (100.0%)

10 (100.0%)

6 (100.0%)

0.756

 No

1 (4.5%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

SUVmax

10.9 ± 4.5

6.7 ± 2.4

7.9 ± 3.6

8.4 ± 1.6

0.008

  1. GCTB giant-cell tumor of bone, LCH langerhans cell histiocytosis, SUVmax maximum standard uptake value.