Table 2 Key diagnostic points of intermediate bone tumors of different pathologic types.
From: 18F-FDG PET/CT findings of intermediate bone tumors of the spine
Tumor types | Onset age | Location | PET/CT findings | |
|---|---|---|---|---|
CT features | PET features | |||
GCTB | Prefer middle-aged patients | More common in thoracic vertebrae and sacral vertebrae | Lesions are predominantly centered in the vertebral body, with incomplete cortex, eccentric expansile bone destruction and soft tissue mass; a sclerotic rim may rarely be observed | Obviously increased 18F-FDG uptake |
Osteoblastoma | Prefer young patients | More common in cervical and lumbar spine | Lesions are typically centered in posterior elements, with complete bone cortex; soft tissue masses, residual bony ridges/calcifications, and sclerotic rims in most cases | Increased 18F-FDG uptake |
LCH | Prefer middle-aged patients | More common in thoracic vertebra and cervical vertebra | Lesions are predominantly centered within the vertebral body, which may also exhibit eccentric expansile osteolytic destruction and soft tissue mass; but most of the diseased vertebral bodies are not accompanied by vertebral compression, and the lesions in the stable period can present sclerotic rim. | Active lesions demonstrate increased 18F-FDG uptake, while stable lesions typically show no significant uptake. |
Epithelioid hemangioma | Prefer middle-aged patients | More common in thoracic vertebra | Similar to GCTB, lesions are predominantly centered in the vertebral body, with incomplete cortex, eccentric expansile bone destruction and soft tissue mass; but with rare sclerotic rim | Increased 18F-FDG uptake |
