Fig. 5
From: Oxygen level alters energy metabolism in bovine preimplantation embryos
Comparison of blastocysts transcriptomic profiles grown under hypoxia, normoxia and ultrahypoxia. (A) Volcano plot representation of the transcriptional difference in the blastocysts grown under hypoxia against 16-cell stage hypoxia embryos. (B) Volcano plot representation of the transcriptional difference in the blastocysts grown under normoxia against 16-cell stage normoxia embryos. (C) Volcano plot representation of the transcriptional difference in the blastocysts grown under ultrahypoxia against 16-cell stage hypoxia embryos. Downregulated genes are shown in brown, not significant in grey and upregulated genes in green. (D) Number of differentially expressed genes (DEG) in blastocysts against 16-cell embryos across the 3 experimental conditions. (E) Chord diagram of the KEGG pathways upregulated at the blastocysts stage against 16-cell stage embryos in all 3 conditions, showing which KEGG pathways are shared between all 3 conditions (pink), only in hypoxia and ultrahypoxia (beige), only in hypoxia (purple), only in ultrahypoxia (green) and only in normoxia (yellow) marked as NO on the figure.
