Fig. 2
From: Safety profile of sikamat virus and its oncolytic potential in leukemic cells and cancer stem cells


PRV7S propagates without causing persistent infection. (a–d) Representative micrographs of infected and non-infected THP1 and K562 cells over time. The complete medium was refreshed at 5 and 11 dpi. Scale bar: 200 μm. (e) Extracellular virus titre of PRV7S was determined using end-point dilution TCID50 assay. (f) Intracellular viral RNA of PRV7S was measured using qRT-PCR. (e,f) Data are presented as mean ± SD. Four independent experiments were performed, each with four replicates.